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Toxicities associated with checkpoint inhibitors-an overview

Dec 1, 2019 ... Immunotherapy has an increasing role in the management of cancer, both in metastatic disease and as an adjuvant therapy.
pubmed.ncbi.nlm.nih.gov/31816085/

Management of Immune-Related Adverse Events in Patients ...

Feb 14, 2018 ... Immune checkpoint inhibitors (ICPis) have revolutionized the treatment of ... With the increasing use of immunotherapy in cancer treatment ...
ascopubs.org/doi/10.1200/jco.2017.77.6385

Toxicities associated with checkpoint inhibitors—an overview - PMC

Dec 9, 2019 ... Patients typically present acutely with weight loss, nausea, fatigue, polyuria and polydipsia. In addition to new cases, CPIs can cause ...
www.ncbi.nlm.nih.gov/pmc/articles/PMC6900917/

Cardiovascular toxicities associated with immune checkpoint ...

Nov 12, 2018 ... Melanoma Fund; and the Melanoma Research Foundation. Introduction. Immune checkpoint inhibitors (ICIs) have improved clinical outcomes in ...
www.thelancet.com/journals/lanonc/article/PIIS1470...

Managing toxicities associated with immune checkpoint inhibitors ...

Nov 21, 2017 ... The most common lung toxicity observed in patients receiving ICI treatment is pneumonitis. The overall incidence of pneumonitis associated with ...
jitc.biomedcentral.com/articles/10.1186/s40425-017...

Immune-checkpoint inhibitors: long-term implications of toxicity ...

Jan 26, 2022 ... Such effects often resolve on treatment withdrawal and/or steroids b, c | Burnout toxicities characterized by irreversible damage to the ...
www.nature.com/articles/s41571-022-00600-w

Toxicities associated with checkpoint inhibitor immunotherapy ...

Aug 18, 2022 ... Despite important clinical benefits, checkpoint inhibitor immunotherapy is associated with a unique spectrum of side effects known as ...
www.uptodate.com/.../toxicities-associated-with-ch...

Mechanisms of Cardiovascular Toxicities Associated With ...

May 3, 2021 ... Immunotherapies include immune checkpoint inhibitors, chimeric antigen receptor (CAR) T-cell therapy, bispecific T-cell engaging antibodies, ...
www.ahajournals.org/doi/10.1161/CIRCRESAHA.120.315...

Evolving insights into the mechanisms of toxicity associated with ...

Jun 16, 2020 ... Immune checkpoint inhibitors have emerged as a revolutionary treatment option for patients with various types of malignancy.
bpspubs.onlinelibrary.wiley.com/doi/10.1111/bcp.14...

Neurologic Toxicity of Immune Checkpoint Inhibitors: A ... - Frontiers

Feb 14, 2022 ... Moreira et al. (2019) found that, in 20 of the 38 (54%) patients, other organ systems were also affected by irAEs: thyroiditis (13% of all cases) ...
www.frontiersin.org/articles/10.3389/fphar.2022.77...